Activation of Estrogen Receptor by Bavachin from Psoralea corylifolia
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چکیده
منابع مشابه
Activation of Estrogen Receptor by Bavachin from Psoralea corylifolia
In this study, we examined the estrogenic activity of bavachin, a component of Psoralea corylifolia that has been used as a traditional medicine in Asia. Bavachin was purified from ethanolic extract of Psoralea corylifolia and characterized its estrogenic activity by ligand binding, reporter gene activation, and endogenous estrogen receptor (ER) target gene regulation. Bavachin showed ER ligand...
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The fruit of Psoralea corylifolia L. (Fabaceae) (PC), known as "Bo-Gol-Zhee" in Korea has been used as traditional medicine. Ethanol and aqueous extracts of PC have an anti-hyperglycemic effect by increasing plasma insulin levels and decreasing blood glucose and total plasma cholesterol levels in type 2 diabetic rats. In this study, we purified six compounds from PC and investigated their anti-...
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The seeds of Psoralea corylifolia Linn. (Fabaceae) have been used extensively as a remedy for leucoderma and Vitiligo. A number of compounds have been isolated from the seeds like furocoumarins, chalcones, flavonoids, terpenoids etc.. We have reported the cytotoxic and antitumour properties of the hexane extract of the seeds of P.corylifolia. The present investigation reports the identification...
متن کاملThe presence of three isoflavonoid compounds in Psoralea corylifolia.
The optimization of a high-performance liquid chromatographic method to determine three isoflavonoids (daidzein, genistein, and biochanin A) in the fruit of Psoralea corylifolia is developed and validated. Dried psoralea fruit powder is extracted with aqueous methanol followed by the hydrolysis of the analytes' conjugated glycosides with hydrochloric acid. The HPLC assay is performed on a rever...
متن کاملAntioxidant, Hemolytic and Mutagenic Potential of Psoralea Corylifolia
Plants are one of the natural sources of bioactive molecules with potential abilities against different stress conditions. During pathogenic exposure, an array of biologically active molecules like reactive oxygen intermediates, phytoalexins and defense peptides are synthesized as measure of plant resistance to combat the intensifying conditions. Such molecules play a key role in advancement in...
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ژورنال
عنوان ژورنال: Biomolecules and Therapeutics
سال: 2012
ISSN: 1976-9148
DOI: 10.4062/biomolther.2012.20.2.183